By alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 23 March 2021 Immunofluorescence image of toxic alpha-synuclein aggregates (green) accumulating in astrocytes (purple). The nuclei of the cells are shown in blue. Credit: Laurent Roybon. In a collaborative study, with other European research groups, scientists from Lund University in Sweden have shed new light on how

https://www.multipark.lu.se/article/new-insights-toxic-protein-aggregate-formation-parkinsons-disease-size-matters - 2025-07-09

By Martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 8 April 2021 On the last of December, Professor Gunnar Gouras left his position as a coordinator for MultiPark after five years. Here is how he sums up his time and mission for our environment. Can you describe your time as a coordinator for Multipark? To lead Multipark has been very interesting as well as challeng

https://www.multipark.lu.se/article/interview-gunnar-gouras-about-his-time-coordinator - 2025-07-09

By Alexander [dot] Doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 12 April 2021 Prof. Malin Parmar (right) with researcher Tiago Cardoso (left). Photo credit: Kennet Ruona. Congratulations to Prof. Malin Parmar, who has been elected as one of three new members of the Board of Directors at the International Society for Stem Cell Research (ISSCR). The Developmental and Regenerative N

https://www.multipark.lu.se/article/malin-parmar-elected-isscr-board-directors - 2025-07-09

By tove [dot] gilvad [at] med [dot] lu [dot] se (Tove Gilvad) - published 29 April 2021 Tau accumulation in different brain regions depending on the subtype of Alzheimer’s disease. Photo: J Vogel Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that l

https://www.multipark.lu.se/article/alzheimers-disease-composed-four-distinct-subtypes - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 3 May 2021 On May 11, it is time for the first of a total of six workshops concerning the strategic research areas’ (SRA) work on sustainable development. Sustainability is more than climate and environmental issues. Goal number 3 of the UN global sustainability goals focuses on “good health and well-being”. The wo

https://www.multipark.lu.se/article/workshop-series-sustainability-effect-research - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 17 May 2021 The study is based on in-depth interviews where patients in an early stage of Parkinson’s disease freely describe their life satisfaction and adaptation to the disease. (Photo: Lina Rosengren) Deep interviews with patients who are at an early stage of Parkinson’s disease show that acceptance was a prere

https://www.multipark.lu.se/article/acceptance-key-life-satisfaction-persons-parkinsons-disease - 2025-07-09

By Martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 19 May 2021 Nine senior researchers from five different faculties at Lund University have been granted three million SEK for a novel transdisciplinary initiative to improve the early diagnosis of Alzheimer’s disease. Four of them are research leaders from the strategic research area MultiPark at the Medical Faculty

https://www.multipark.lu.se/article/three-million-new-thematic-collaboration-initiative-about-early-diagnosis-and-prognostics-alzheimers - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 24 May 2021 New study: a simple blood test and three quick cognitive tests show with over 90% certainty who develops Alzheimer's dementia within four years. (The number test in the picture is an example, not exactly what you do in cognitive tests). Illustration: Jona Researchers at Lund University in Sweden have de

https://www.multipark.lu.se/article/simple-diagnostic-tool-predicts-individual-risk-alzheimers - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 27 May 2021 Yiyi Yang defends her PhD thesis on Thursday 3rd June 2021. During her Ph.D. studies, Yiyi Yang has been investigating the role of microglia in the pathological development of Alzheimer’s disease. On the 3rd of June, it is time to defend her work supervised by Prof. Tomas Deierborg. Now, Yiyi tells us a

https://www.multipark.lu.se/article/phd-defence-interview-yiyi-yang - 2025-07-09

By fritzliselotte [at] gmail [dot] com (Liselotte Fritz) - published 1 June 2021 Kajsa Brolin, doctoral student in Translational Neurogenetics at Lund University, is using the biobank in her doctoral thesis. Photo: Kennet Ruona Around 20 000 Swedes are currently suffering from Parkinson’s disease, yet there are still only treatments to alleviate symptoms. Through a new biobank, researchers gain ac

https://www.multipark.lu.se/article/new-biobank-provides-insights-parkinsons-disease - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 8 June 2021 Angela with her team members in the Basal ganglia pathophysiology group. Here, they enjoy spending time together during a before-Corona dinner. On the first of January, Professor Angela Cenci Nilsson took on as the new coordinator for MultiPark. Now she tells us about her visions for our network and abo

https://www.multipark.lu.se/article/interview-angela-cenci-nilsson-about-being-new-coordinator-multipark - 2025-07-09

By filip [dot] backstrom [at] med [dot] lu [dot] se (Filip Bäckström) - published 28 June 2021 Created with BioRender.com T-cells, antibodies, and antigens. During the past year, we have learned a lot about our immune system through media. Most people agree that the immune system is crucial for our survival. But how does the immune system affect Parkinson’s disease; is it necessary to keep our bra

https://www.multipark.lu.se/article/does-our-immune-response-affect-risk-developing-parkinsons-disease - 2025-07-09

By katrin [dot] stahl [at] med [dot] lu [dot] se (Katrin Ståhl) - published 24 August 2021 Photo: Mostphotos An experimental study from Lund University in Sweden has revealed that the Alzheimer’s protein amyloid-beta accumulates inside nerve cells, and that the misfolded protein may then spread from cell to cell via nerve fibres. This happens at an earlier stage than the formation of amyloid-beta

https://www.multipark.lu.se/article/does-alzheimers-disease-start-inside-nerve-cells - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 7 September 2021 The Basal Ganglia Pathophysiology research group has long experience in using established behavioral tests to monitor rodent behavior. This is used in combination with recordings of neuronal activity. Copyright: The Basal Ganglia Pathophysiology group A large collaborative project focused on unders

https://www.multipark.lu.se/article/new-transnational-collaboration-target-circuit-dysfunctions-parkinsons-disease - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 14 September 2021 Photo: Agata Garpenlind A combination of two imaging methods can be used to achieve structural and chemical information within a single neuron. Researchers from MultiPark at Lund University recently developed this approach. Their study reveals that amyloid aggregates, implicated in Alzheimer’s dis

https://www.multipark.lu.se/article/novel-imaging-approach-open-doors-understanding-key-pathological-processes-inside-neurons - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 20 September 2021 Amyloid-beta accumulation may start inside neurons. A novel imaging approach to study structural changes before amyloid plaques are formed. Four distinct subtypes of Alzheimer's disease. A simple diagnostic tool predicting the risk of developing the disease. And a collaboration with Region Skåne,

https://www.multipark.lu.se/article/alzheimers-awareness-month-five-optimistic-research-news-multipark - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 28 September 2021 Anna Hammarberg guides the Ph.D. student Roman Sattarov on how to analyze his sample on the software. A machine allowing researchers to rely on objective, automatized readouts instead of subjective manual counting under the microscope. Incredible pictures. And the possibility to follow live cellul

https://www.multipark.lu.se/article/seven-tones-operetta-multiparks-new-high-content-analysis-platform - 2025-07-09

By agata [dot] garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 11 October 2021 Photo: Mostphotos Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers at Lund University in Sweden have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a differe

https://www.multipark.lu.se/article/what-makes-us-human-answer-may-be-found-overlooked-dna - 2025-07-09

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 14 October 2021 During her thesis project, Nadja Gustavsson has characterized structural changes inside neurons of a new mouse model for mixed neurogenerative disorders. On the 21st of October, she is defending her thesis supervised by Oxana Klementieva. In this interview, Nadja shares her ups and downs during her

https://www.multipark.lu.se/article/phd-defence-interview-nadja-gustavsson - 2025-07-09

By s [dot] thiesen [at] sund [dot] ku [dot] dk (Søren Thiesen) - published 22 October 2021 During pneumococcal meningitis, immune cells produce structures blocking the normal cerebrospinal fluid movement. This illustration was selected as the cover image for Annals of Neurology. Illustration: Chiara Pavan & Dan Xue. Meningitis is a very serious brain infection with limited treatment options. In a

https://www.multipark.lu.se/article/meningitis-researchers-find-possible-treatment-strategy-without-antibiotics - 2025-07-09